Topic
Topic
A Nature paper reports the first direct small-molecule targeting of microphthalmia-associated transcription factor (MITF), the melanoma oncogene long classified as undruggable. Preclinical work is th…
A Frontiers review connects gut dysbiosis to atopic dermatitis via the gut-skin axis and catalogs novel targeted therapeutic stra…
Vismodegib and sonidegib both block Smoothened, yet dosing, tolerability and real-world experience separate the only two FDA-appr…
University of Utah Health reports an investigational drug shows promise in NRAS-driven melanoma, a subtype lacking targeted optio…
A new Frontiers review positions the transcription factor MYC as a convergent, functionally critical target in melanoma, surveyin…
