CAR-T Immunotherapy Clears Psoriasis: A 92.6% PASI Drop
Anti-CD19 CAR-T therapy given for lymphoma produced a 92.6% PASI reduction in a 45-year plaque psoriasis case, fueling review of CAR strategies for immune reset.
Topic
Immunotherapy
Topic
Immunotherapy
JAAD Expert Opinion Weighs Hedgehog Inhibitors in the Immunotherapy Era for Advanced BCC
JAAD published an expert opinion on October 8, 2026 comparing efficacy and tolerability of hedgehog pathway inhibitors for locall…
First Patient Treated in Trial Targeting Immunotherapy Resistance
The Institute of Cancer Research has treated the first patient in a new clinical trial targeting immunotherapy resistance in lung…
MRD-Guided Melanoma Trial Enrolls First Patients With Signatera
First patients enrolled in NCT07504796: Signatera-positive melanoma patients randomized at week six to ipilimumab escalation or c…
IDO1 Inhibitor Fails to Amplify T-Cell Response to Melanoma Vaccine
A clinical trial reports that combining an IDO1 inhibitor with a melanoma vaccine did not increase tumor-fighting T cells, underm…
Real-World Data Back Avelumab in Merkel Cell Carcinoma
Avelumab demonstrates effectiveness against Merkel cell carcinoma in a real-world population, Medscape reports, extending evidenc…
Major Review Maps Persistent Care Gap for Melanoma Survivors
A major review reported by Bioengineer.org maps effective post-treatment interventions for melanoma survivors and identifies an u…
Personalised mRNA Vaccine Stops Melanoma Returning in Reported Breakthrough
A personalised mRNA cancer vaccine stopped melanoma from returning, Gavi reports, marking a milestone for individualised neoantig…
Sequencing Hedgehog Inhibitors with Surgery, Radiation and Immunotherapy in BCC
New Dermatology Times guidance examines how to order hedgehog inhibitors with surgery, radiation and immunotherapy in advanced ba…
Northwestern: Radiotherapy Reshapes Immune Response in Skin Cancer
Northwestern University researchers report that radiotherapy reprograms the immune response in a rare cutaneous malignancy. The i…